ACTINIUM-225, AC-225

Intended use: This is alpha-emitting radionuclide and short-lived product of its dissolution, bismuth-213 (46 minutes); these substances are promising for the treatment of various oncological diseases by means of radiotherapy.

SODIUM IODIDE, I-125

Intended use: Sodium iodide is used in brachytherapy of cancer (prostate and brain), to estimate the glomerular filtration rate and to diagnose deep vein thrombosis, and is also used extensively in the radioimmunoassay.

Sodium Iodide I-131

Indication: Diagnostics and thyroid gland treatment: for  an evaluation of  thyroid gland function, scanning and scintigraphy of thyroid gland at various diseases, including for diagnostics of infringement of  thyroid gland functions, and also small-celled cancer of a thyroid gland and metastasises. With a view of therapy, Sodium iodide I-131 is used  for thyrotoxicosis treatment and metastatic cancer of a thyroid gland.

LUTETIUM CHLORIDE, LU-177

Intended use: Treatment of neuroendocrine tumors with metastases. The drug is intended for IV injections. The patient is also treated with a protective drug to reduce the radiation exposure. The drug has a potent effect in destroying the cancer cells. In some cases, a full recovery occurs, but Lu-177 is mainly used to relieve clinical manifestations of cancer disease.

MOLYBDENUM-99, MO-99

Intended use: The Mo-99 isotope is the parent isotope in the Tc-99m generator, which is used in the diagnosis of oncological diseases to visualize the skeleton and cardiac muscle, as well as to visualize the brain, the thyroid gland, the lungs (perfusion and ventilation), the gallbladder, the bone marrow, as well as the salivary and lacrimal glands.

PHOSPHORUS-32, Р-32

Intended use: Р-32 is used to diagnose brain tumors, intraocular tumors, breast tumors and some others. P-32 can be used to determine the velocity of blood flow, total volume of red blood cells, amount of circulating blood in cardiovascular diseases, and to diagnose the hematological diseases. Р-32 is considered to be the best known means for treatment of polycythemia, with less efficacy in myeloid leukemia. Moreover, radioactive phosphorus is also used in certain malignant neoplasms: Ewing Sarcoma, osteogenic sarcoma, gallbladder cancer, and bone metastases of breast cancer.

SAMARIUM-153, SM-153

Indication: Used in oncology with the aim of a persistent reduction in the intensity of the pain syndrome, caused by the presence of metastatic damage bones and for rheumatic patients with severe pain syndrome. Also Sm-153 is very effective in the diagnosis and treatment of prostate and breast cancer.

STRONTIUM CHLORIDE, SR-89

Intended use: Sr-89 is one of the most effective modern treatment modality, which is used for palliative care in patients with metastatic diasese of prostate, breast, kidneys, and lungs. Sr-89 is also used as an alternative method (or as a additional treatment method combined with external radiation therapy) to relieve the pain syndrome in bone cancer.

TC-99M GENERATOR

Indication: Tc-99m generator is intended for multiple production of sterile pyrogen-free sodium pertechnetate in physiological saline solution (0,9% NaCl).

THALLIUM-201, TL-201

Intended use: This radionuclide is often used to diagnose coronary heart disease and other heart diseases. This is the most commonly used replacement for Tc-99m. Tl-201 was the main substance for the nuclear cardiography. Moreover, this radionuclide is still being used for stress tests in patient with high risk of coronary heart disease.

Sodium tungstate, W-188

Intended use: W-188 is a parent isotope for the production of W-188/Re-188 generators, designed to produce sterile apyrogenic sodium perrhenate Na¹⁸⁸ReO₄), which, combined with special kits, is used to synthesize the radiopharmaceutical agents for cancer therapy with simultaneous visualization of the distribution of the agent in the human body.

XENON-133, XE-133

Intended use: In clinical settings, Xe-133 is used for radioisotope diagnostics in the form of an air-xenon mixture and an isotonic solution. Air-xenon (Xe-133) mixture is used as a radioactive indicator in the study of regional pulmonary ventilation, to assess the patency of subarachnoid space and to determine the level and degree of blockade of CSF pathways of the spinal cord. Sterile isotonic solution with Xe-133 is used for quantitative assessment of blood flow in various organs and tissues. In clinical settings, this technique has widely used in evaluation of regional cerebral bloodflow, muscular bloodflow, coronary blood flow, as well as regional bloodflow in the lungs.